Journal of Cerebrovascular Disease 2020 Vol.3 No.2 10-14

Neuroendoscopy Combined with Lateral Ventricle Drainage and Urokinase Infusion in the Treatment of 20 Patients with Hypertensive Intraventricular Hemorrhage

Author(s): Guo-Dong Qian1,Xiao-Xu Shen1,Jian Xu1,Wei-Hua Xu1,Dong Zhao1,Yang Wang1,Qi Liu1

Affiliation(s): 1Department of Neurosurgery, The First Affiliated Hospital of Medical College, Shihezi University

Corresponding Author: Qi Liu

Corresponding email(s):

Key Words: Neuroendoscopy; Intraventricular hemorrhage; Lateral ventricle drainage; Urokinase perfusion


Objective: To explore the clinical efficacy of neuroendoscopy combined with lateral ventricle drainage and urokinase infusion for the treatment of hypertensive intraventricular hemorrhage.

Methods: A retrospective analysis of 20 patients diagnosed with intraventricular hemorrhage between March 2017 and August 2018 at the First Affiliated Hospital of Medical College, Shihezi University (Shiohezi, China) was performed. While actively treating primary lesions, 20 patients with intraventricular hemorrhage were selected and treated using minimally invasive neuroendoscopic removal of intraventricular hematoma combined with lateral ventricular drainage and urokinase perfusion according to each patient’s condition.

Results: One day after surgery, head computed tomography examination revealed that > 50% of the hematoma in the lateral ventricle was removed in 14 cases, and 20%-50% of the hematoma in the other 6 cases. After follow-up, 13 patients exhibited satisfactory recovery, 5 died (3 due to lung infection, 1 due to intracranial infection, and 1 due to multiple organ failure), and 2 were in a vegetative state.

Conclusion: Neuroendoscopy should be used as much as possible in treating intraventricular hemorrhage given its advantages of minimal injury, complete removal of hematoma, high safety, and wide clinical applicability.

Full Text: 

On-line Access: 2019-08-01

Received: 2019-04-05

Revision Accepted: 2019-06-19

Publish: 2020-06-01

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